A master student position will be available within the Special Research Program SFB-54: "InThro", which allows to establish a network of eight research groups, focusing on molecular and cellular links between inflammation and thrombotic diseases.

Thromboses of the venous or the arterial system are a serious health problem nowadays. Certain diseases are known to increase the risk for venous and arterial thromboses considerably and this is specifically true for cancer. Recent studies have identified factors that contribute to thrombosis development in patients with cancer. These include tissue factor-positive extracellular vesicles (TF+EVs) and neutrophil extracellular traps (NETs). It is the aim of this master thesis to analyse the phenotype of immune cells and platelets from patients with cancer compared to healthy controls, as well as to analyse the interplay between immune cells, platelets, TF+EVs and NETs in vitro to extend our knowledge on thrombosis development in patients with cancer. Methods within this master thesis will include cell culture, isolation of different blood cell types, phenotype and activation studies with different immune cells, ELISA and flow cytometry.

The applicant should have a Bachelor degree or equivalent degree in Life Sciences or Biochemistry or Molecular Biology. Experience with basic techniques used in Molecular Biology and with the use of basic computer software is desirable. The applicant should be interested in applied research, show an independent working-style and work very precisely.

Thesis duration: 9 Month

Beginning: September/October 2019

Applications including a detailed CV and relevant diplomas should be sent by email to:

Univ.Prof. Dr. Ingrid Pabinger and Lena Hell, PhD

Medizinische Universität Wien

Universitätsklinik für Innere Medizin I

Währinger Gürtel 18-20

A-1090 Vienna,

Austria

Mail: lena.hell@meduniwien.ac.at

Master positions are available for the Special Research Program SFB-F54 of the Austrian Science Fund (“Cellular Mediators Linking Inflammation and Thrombosis”; http://inthro.meduniwien.ac.at/?L=0) in the group of Prof. Johannes Schmid.

The master students will be integrated in a highly cooperative, supportive team with friendly working environment.

The main field of our research is vascular biology and thrombosis research. In general, we focus on the role of inflammation in the development of certain disease models like atherosclerosis, liver steatosis, and lung fibrosis.

Depending on the specific project, the work will include cell culture (endothelial cells, macrophages, megakaryocytes, platelets), animal work, analysis of clinical samples, microscopy, flow cytometry and RNA/protein analysis.

If you are interested to apply and to become part of our (cake-loving) team, please visit our website and send your Application and Curriculum Vitae to the following mail address: marion.mussbacher@meduniwien.ac.at.